Difference between revisions of "YML029W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004491 YML029W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004491 YML029W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''USA1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''USA1 ''
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'''Description of YML029W:''' Protein involved in ER-associated protein degradation (ERAD); component of the Hrd1p complex; interacts with the U1 snRNP-specific protein, Snp1p<ref name='S000069169'>Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 {{SGDpaper|S000069169}} PMID 11425851</ref><ref name='S000117399'>Carvalho P, et al. (2006) Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell 126(2):361-73
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'''Description of YML029W:''' Scaffold subunit of the Hrd1p ubiquitin ligase that also promotes ligase oligomerization; involved in ER-associated protein degradation (ERAD); interacts with the U1 snRNP-specific protein, Snp1p<ref name='S000069169'>Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 {{SGDpaper|S000069169}} PMID 11425851</ref><ref name='S000117399'>Carvalho P, et al. (2006) Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell 126(2):361-73 {{SGDpaper|S000117399}} PMID 16873066</ref><ref name='S000134843'>Horn SC, et al. (2009) Usa1 functions as a scaffold of the HRD-ubiquitin ligase. Mol Cell 36(5):782-93
  {{SGDpaper|S000117399}} PMID 16873066</ref>
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  {{SGDpaper|S000134843}} PMID 20005842</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YML029W
Gene name USA1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:217362..219878
Primary SGDID S000004491


Description of YML029W: Scaffold subunit of the Hrd1p ubiquitin ligase that also promotes ligase oligomerization; involved in ER-associated protein degradation (ERAD); interacts with the U1 snRNP-specific protein, Snp1p[1][2][3]




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References

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  1. Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 SGD PMID 11425851
  2. Carvalho P, et al. (2006) Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell 126(2):361-73 SGD PMID 16873066
  3. Horn SC, et al. (2009) Usa1 functions as a scaffold of the HRD-ubiquitin ligase. Mol Cell 36(5):782-93 SGD PMID 20005842

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