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Systematic name YML007W
Gene name YAP1
Aliases PAR1, SNQ3
Feature type ORF, Verified
Coordinates Chr XIII:253848..255800
Primary SGDID S000004466

Description of YML007W: Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; mediates resistance to cadmium[1][2][3][4]


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  1. Kuge S, et al. (1997) Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J 16(7):1710-20 SGD PMID 9130715
  2. Moye-Rowley WS, et al. (1989) Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins. Genes Dev 3(3):283-92 SGD PMID 2542125
  3. Okazaki S, et al. (2007) Multistep disulfide bond formation in Yap1 is required for sensing and transduction of H(2)O(2) stress signal. Mol Cell 27(4):675-88 SGD PMID 17707237
  4. Wu A, et al. (1993) Yeast bZip proteins mediate pleiotropic drug and metal resistance. J Biol Chem 268(25):18850-8 SGD PMID 8360174

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