Difference between revisions of "YLR135W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004125 YLR135W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SLX4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SLX4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:413281..415527 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004125 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004125 | ||
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| − | '''Description of YLR135W:''' | + | '''Description of YLR135W:''' Endonuclease involved in processing DNA during recombination and repair; cleaves branched structures in a complex with Slx1p; involved in Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing<ref name='S000073797'>Fricke WM and Brill SJ (2003) Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3. Genes Dev 17(14):1768-78 {{SGDpaper|S000073797}} PMID 12832395</ref><ref name='S000126454'>Li F, et al. (2008) Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates. Mol Cell 30(3):325-35 |
| − | {{SGDpaper| | + | {{SGDpaper|S000126454}} PMID 18471978</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YLR135W |
| Gene name | SLX4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:413281..415527 |
| Primary SGDID | S000004125 |
Description of YLR135W: Endonuclease involved in processing DNA during recombination and repair; cleaves branched structures in a complex with Slx1p; involved in Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing[1][2]
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References
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- ↑ Fricke WM and Brill SJ (2003) Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3. Genes Dev 17(14):1768-78 SGD PMID 12832395
- ↑ Li F, et al. (2008) Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates. Mol Cell 30(3):325-35 SGD PMID 18471978
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