YLR086W
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| Systematic name | YLR086W |
| Gene name | SMC4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:302244..306500 |
Description of YLR086W: Subunit of the condensin complex, which reorganizes chromosomes during cell division, forms a stable complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity and promotes knotting of circular DNA; potential Cdc28p substrate[1][2]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [3]
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References
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- ↑ 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Stray JE and Lindsley JE (2003) Biochemical analysis of the yeast condensin Smc2/4 complex: an ATPase that promotes knotting of circular DNA. J Biol Chem 278(28):26238-48 SGD PMID 12719426
- ↑ submitted by Jeff Ubersax on 2004-01-29
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