YKL193C

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Systematic name YKL193C
Gene name SDS22
Aliases EGP1
Feature type ORF, Verified
Coordinates Chr XI:79882..78866
Primary SGDID S000001676


Description of YKL193C: Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis[1][2][3][4][5]




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References

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  1. Hisamoto N, et al. (1995) The EGP1 gene may be a positive regulator of protein phosphatase type 1 in the growth control of Saccharomyces cerevisiae. Mol Cell Biol 15(7):3767-76 SGD PMID 7791784
  2. Hong G, et al. (2000) Sds22p is a subunit of a stable isolatable form of protein phosphatase 1 (Glc7p) from Saccharomyces cerevisiae. Arch Biochem Biophys 376(2):288-98 SGD PMID 10775415
  3. MacKelvie SH, et al. (1995) The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase. Mol Cell Biol 15(7):3777-85 SGD PMID 7791785
  4. Peggie MW, et al. (2002) Essential functions of Sds22p in chromosome stability and nuclear localization of PP1. J Cell Sci 115(Pt 1):195-206 SGD PMID 11801737
  5. Ramaswamy NT, et al. (1998) Regulation of yeast glycogen metabolism and sporulation by Glc7p protein phosphatase. Genetics 149(1):57-72 SGD PMID 9584086

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