Difference between revisions of "YKL193C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YKL193C YKL193C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001676 YKL193C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SDS22 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SDS22 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr XI:79887..78871
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|nowrap| Chr XI:79882..78866
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001676
 
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'''Description of {{PAGENAME}}:''' Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis<ref name='S000069049'>Peggie MW, et al. (2002) Essential functions of Sds22p in chromosome stability and nuclear localization of PP1. J Cell Sci 115(Pt 1):195-206 {{SGDpaper|S000069049}} PMID 11801737</ref><ref name='S000043932'>Ramaswamy NT, et al. (1998) Regulation of yeast glycogen metabolism and sporulation by Glc7p protein phosphatase. Genetics 149(1):57-72 {{SGDpaper|S000043932}} PMID 9584086</ref><ref name='S000041881'>Hong G, et al. (2000) Sds22p is a subunit of a stable isolatable form of protein phosphatase 1 (Glc7p) from Saccharomyces cerevisiae. Arch Biochem Biophys 376(2):288-98 {{SGDpaper|S000041881}} PMID 10775415</ref><ref name='S000040716'>MacKelvie SH, et al. (1995) The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase. Mol Cell Biol 15(7):3777-85 {{SGDpaper|S000040716}} PMID 7791785</ref><ref name='S000040713'>Hisamoto N, et al. (1995) The EGP1 gene may be a positive regulator of protein phosphatase type 1 in the growth control of Saccharomyces cerevisiae. Mol Cell Biol 15(7):3767-76
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'''Description of YKL193C:''' Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p; whether it functions as a positive or negative regulator of Glc7p is controversial; involved in the regulation of Glc7p nuclear localization and function<ref name='S000125078'>Bharucha JP, et al. (2008) Ypi1, a Positive Regulator of Nuclear Protein Phosphatase Type 1 Activity in Saccharomyces cerevisiae. Mol Biol Cell 19(3):1032-45 {{SGDpaper|S000125078}} PMID 18172024</ref><ref name='S000040713'>Hisamoto N, et al. (1995) The EGP1 gene may be a positive regulator of protein phosphatase type 1 in the growth control of Saccharomyces cerevisiae. Mol Cell Biol 15(7):3767-76 {{SGDpaper|S000040713}} PMID 7791784</ref><ref name='S000041881'>Hong G, et al. (2000) Sds22p is a subunit of a stable isolatable form of protein phosphatase 1 (Glc7p) from Saccharomyces cerevisiae. Arch Biochem Biophys 376(2):288-98 {{SGDpaper|S000041881}} PMID 10775415</ref><ref name='S000040716'>MacKelvie SH, et al. (1995) The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase. Mol Cell Biol 15(7):3777-85 {{SGDpaper|S000040716}} PMID 7791785</ref><ref name='S000119975'>Pedelini L, et al. (2007) YPI1 and SDS22 proteins regulate the nuclear localization and function of yeast type 1 phosphatase Glc7. J Biol Chem 282(5):3282-92 {{SGDpaper|S000119975}} PMID 17142459</ref><ref name='S000069049'>Peggie MW, et al. (2002) Essential functions of Sds22p in chromosome stability and nuclear localization of PP1. J Cell Sci 115(Pt 1):195-206 {{SGDpaper|S000069049}} PMID 11801737</ref><ref name='S000043932'>Ramaswamy NT, et al. (1998) Regulation of yeast glycogen metabolism and sporulation by Glc7p protein phosphatase. Genetics 149(1):57-72
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==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 14:05, 3 May 2012

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Systematic name YKL193C
Gene name SDS22
Aliases EGP1
Feature type ORF, Verified
Coordinates Chr XI:79882..78866
Primary SGDID S000001676


Description of YKL193C: Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p; whether it functions as a positive or negative regulator of Glc7p is controversial; involved in the regulation of Glc7p nuclear localization and function[1][2][3][4][5][6][7]




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References

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  1. ↑ Bharucha JP, et al. (2008) Ypi1, a Positive Regulator of Nuclear Protein Phosphatase Type 1 Activity in Saccharomyces cerevisiae. Mol Biol Cell 19(3):1032-45 SGD PMID 18172024
  2. ↑ Hisamoto N, et al. (1995) The EGP1 gene may be a positive regulator of protein phosphatase type 1 in the growth control of Saccharomyces cerevisiae. Mol Cell Biol 15(7):3767-76 SGD PMID 7791784
  3. ↑ Hong G, et al. (2000) Sds22p is a subunit of a stable isolatable form of protein phosphatase 1 (Glc7p) from Saccharomyces cerevisiae. Arch Biochem Biophys 376(2):288-98 SGD PMID 10775415
  4. ↑ MacKelvie SH, et al. (1995) The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase. Mol Cell Biol 15(7):3777-85 SGD PMID 7791785
  5. ↑ Pedelini L, et al. (2007) YPI1 and SDS22 proteins regulate the nuclear localization and function of yeast type 1 phosphatase Glc7. J Biol Chem 282(5):3282-92 SGD PMID 17142459
  6. ↑ Peggie MW, et al. (2002) Essential functions of Sds22p in chromosome stability and nuclear localization of PP1. J Cell Sci 115(Pt 1):195-206 SGD PMID 11801737
  7. ↑ Ramaswamy NT, et al. (1998) Regulation of yeast glycogen metabolism and sporulation by Glc7p protein phosphatase. Genetics 149(1):57-72 SGD PMID 9584086

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