YJR110W

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Systematic name YJR110W
Gene name YMR1
Aliases
Feature type ORF, Verified
Coordinates Chr X:633609..635675


Description of YJR110W: Phosphatidylinositol 3-phosphate [PI(3)P] phosphatase, regulates the localization and levels of PI(3)P; involved in cytoplasm to vacuole (CVT) transport; has similarity to the conserved myotubularin dual specificity phosphatase family[1][2]




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References

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  1. Parrish WR, et al. (2004) Essential role for the myotubularin-related phosphatase Ymr1p and the synaptojanin-like phosphatases Sjl2p and Sjl3p in regulation of phosphatidylinositol 3-phosphate in yeast. Mol Biol Cell 15(8):3567-79 SGD PMID 15169871
  2. Taylor GS, et al. (2000) Inaugural article: myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate. Proc Natl Acad Sci U S A 97(16):8910-5 SGD PMID 10900271

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