Difference between revisions of "YJL101C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YJL101C
Gene name GSH1
Aliases
Feature type ORF, Verified
Coordinates Chr X:236352..234316


Description of YJL101C: Gamma glutamylcysteine synthetase, catalyzes the first step in the gamma-glutamyl cycle for glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury[1][2][3][4][5]




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References

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  1. Westwater J, et al. (2002) The adaptive response of Saccharomyces cerevisiae to mercury exposure. Yeast 19(3):233-9 SGD PMID 11816031
  2. Stephen DW and Jamieson DJ (1997) Amino acid-dependent regulation of the Saccharomyces cerevisiae GSH1 gene by hydrogen peroxide. Mol Microbiol 23(2):203-10 SGD PMID 9044254
  3. Kistler M, et al. (1990) Genetic and biochemical analysis of glutathione-deficient mutants of Saccharomyces cerevisiae. Mutagenesis 5(1):39-44 SGD PMID 2184310
  4. Ohtake Y and Yabuuchi S (1991) Molecular cloning of the gamma-glutamylcysteine synthetase gene of Saccharomyces cerevisiae. Yeast 7(9):953-61 SGD PMID 1687097
  5. Stephen DW, et al. (1995) The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae. Mol Microbiol 16(3):415-23 SGD PMID 7565103

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