YJL097W
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| Systematic name | YJL097W |
| Gene name | PHS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:245586..246239 |
| Primary SGDID | S000003633 |
Description of YJL097W: Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane, involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking[1][2][3]
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References
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- ↑ Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 SGD PMID 16269340
- ↑ Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 SGD PMID 16943325
- ↑ Kihara A, et al. (2008) Membrane Topology and Essential Amino Acid Residues of Phs1, a 3-Hydroxyacyl-CoA Dehydratase Involved in Very Long-chain Fatty Acid Elongation. J Biol Chem 283(17):11199-209 SGD PMID 18272525
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