Difference between revisions of "YIR033W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001472 YIR033W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MGA2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MGA2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IX: | + | |nowrap| Chr IX:416124..419465 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001472 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001472 | ||
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| − | '''Description of YIR033W:''' ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting | + | '''Description of YIR033W:''' ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting<ref name='S000066217'>Chellappa R, et al. (2001) The membrane proteins, Spt23p and Mga2p, play distinct roles in the activation of Saccharomyces cerevisiae OLE1 gene expression. Fatty acid-mediated regulation of Mga2p activity is independent of its proteolytic processing into a soluble transcription activator. J Biol Chem 276(47):43548-56 {{SGDpaper|S000066217}} PMID 11557770</ref><ref name='S000073474'>Shcherbik N, et al. (2003) Rsp5p is required for ER bound Mga2p120 polyubiquitination and release of the processed/tethered transactivator Mga2p90. Curr Biol 13(14):1227-33 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073474}} PMID 12867034</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YIR033W |
| Gene name | MGA2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:416124..419465 |
| Primary SGDID | S000001472 |
Description of YIR033W: ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting[1][2]
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References
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- ↑ Chellappa R, et al. (2001) The membrane proteins, Spt23p and Mga2p, play distinct roles in the activation of Saccharomyces cerevisiae OLE1 gene expression. Fatty acid-mediated regulation of Mga2p activity is independent of its proteolytic processing into a soluble transcription activator. J Biol Chem 276(47):43548-56 SGD PMID 11557770
- ↑ Shcherbik N, et al. (2003) Rsp5p is required for ER bound Mga2p120 polyubiquitination and release of the processed/tethered transactivator Mga2p90. Curr Biol 13(14):1227-33 SGD PMID 12867034
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