YIL046W

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Systematic name YIL046W
Gene name MET30
Aliases ZRG11
Feature type ORF, Verified
Coordinates Chr IX:268650..270572
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Description of YIL046W: F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus[1][2]



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References

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  1. Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52 SGD PMID 11027256
  2. Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94 SGD PMID 10637232

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