Difference between revisions of "YHR098C"
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| − | '''Description of YHR098C:''' | + | '''Description of YHR098C:''' Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sec24p and Sfb2p<ref name='S000049853'>Roberg KJ, et al. (1999) LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum. J Cell Biol 145(4):659-72 {{SGDpaper|S000049853}} PMID 10330397</ref><ref name='S000059360'>Shimoni Y, et al. (2000) Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J Cell Biol 151(5):973-84 {{SGDpaper|S000059360}} PMID 11086000</ref><ref name='S000071975'>Miller E, et al. (2002) Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J 21(22):6105-13 {{SGDpaper|S000071975}} PMID 12426382</ref><ref name='S000074170'>Miller EA, et al. (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114(4):497-509 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074170}} PMID 12941277</ref> |
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Revision as of 14:05, 8 January 2010
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| Systematic name | YHR098C |
| Gene name | SFB3 |
| Aliases | LST1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:301937..299148 |
| Primary SGDID | S000001140 |
Description of YHR098C: Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sec24p and Sfb2p[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Roberg KJ, et al. (1999) LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum. J Cell Biol 145(4):659-72 SGD PMID 10330397
- ↑ Shimoni Y, et al. (2000) Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J Cell Biol 151(5):973-84 SGD PMID 11086000
- ↑ Miller E, et al. (2002) Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J 21(22):6105-13 SGD PMID 12426382
- ↑ Miller EA, et al. (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114(4):497-509 SGD PMID 12941277
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-27
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