YHR079C
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| Systematic name | YHR079C | |
| Gene name | IRE1 | |
| Aliases | ERN1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr VIII:261593..258246 | |
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Description of YHR079C: Serine-threonine kinase and endoribonuclease; transmembrane protein that initiates the unfolded protein response signal by regulating synthesis of Hac1p through HAC1 mRNA splicing[1][2]
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References
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- ↑ Welihinda AA and Kaufman RJ (1996) The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation. J Biol Chem 271(30):18181-7 SGD PMID 8663458
- ↑ Sidrauski C and Walter P (1997) The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90(6):1031-9 SGD PMID 9323131
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