Difference between revisions of "YHR037W"

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'''Description of YHR037W:''' Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism<ref name='S000044204'>Brandriss MC (1983) Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT2 gene. Mol Cell Biol 3(10):1846-56 {{SGDpaper|S000044204}} PMID 6358862</ref><ref name='S000057841'>Hu CA, et al. (1996) Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase. J Biol Chem 271(16):9795-800
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'''Description of YHR037W:''' Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism<ref name='S000057841'>Hu CA, et al. (1996) Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase. J Biol Chem 271(16):9795-800 {{SGDpaper|S000057841}} PMID 8621661</ref><ref name='S000044204'>Brandriss MC (1983) Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT2 gene. Mol Cell Biol 3(10):1846-56
  {{SGDpaper|S000057841}} PMID 8621661</ref>
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  {{SGDpaper|S000044204}} PMID 6358862</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YHR037W
Gene name PUT2
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:181970..183697
Primary SGDID S000001079


Description of YHR037W: Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism[1][2]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in nitrogen limited chemostat cultures versus nitrogen excess. [3] [4]





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References

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  1. Hu CA, et al. (1996) Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase. J Biol Chem 271(16):9795-800 SGD PMID 8621661
  2. Brandriss MC (1983) Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT2 gene. Mol Cell Biol 3(10):1846-56 SGD PMID 6358862
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25

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