Difference between revisions of "YHR023W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YHR023W YHR023W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001065 YHR023W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MYO1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MYO1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VIII:151659..157445
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|nowrap| Chr VIII:151666..157452
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001065
 
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'''Description of {{PAGENAME}}:''' Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively<ref name='S000076268'>Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 {{SGDpaper|S000076268}} PMID 15210731</ref><ref name='S000072680'>Tolliday N, et al. (2003) Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Mol Biol Cell 14(2):798-809 {{SGDpaper|S000072680}} PMID 12589071</ref><ref name='S000060912'>Brown SS (1997) Myosins in yeast. Curr Opin Cell Biol 9(1):44-8 {{SGDpaper|S000060912}} PMID 9013666</ref><ref name='S000053564'>Bi E, et al. (1998) Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. J Cell Biol 142(5):1301-12
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'''Description of YHR023W:''' Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively<ref name='S000053564'>Bi E, et al. (1998) Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. J Cell Biol 142(5):1301-12 {{SGDpaper|S000053564}} PMID 9732290</ref><ref name='S000060912'>Brown SS (1997) Myosins in yeast. Curr Opin Cell Biol 9(1):44-8 {{SGDpaper|S000060912}} PMID 9013666</ref><ref name='S000076268'>Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 {{SGDpaper|S000076268}} PMID 15210731</ref><ref name='S000072680'>Tolliday N, et al. (2003) Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Mol Biol Cell 14(2):798-809
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{{SGDpaper|S000072680}} PMID 12589071</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Genetic ====
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[[Category:Topic:Interactions:Genetic]]
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Genetic interaction with hof1 [[Category:Genetic Interactions with hof1]]<br>'''Phenotype(s)''': Synthetic Lethal with hof1 [[Category:Phenotype:Synthetic Lethal with hof1]]
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'''Mutation type(s)''': deletion, deletion
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<ref name='S000040799'>Vallen EA, et al. (2000) Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae. Mol Biol Cell 11(2):593-611 {{SGDpaper|S000040799}} PMID 10679017</ref> <ref name = 'CAset448-2003-08-14'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=448 Erfei Bi] on 2003-08-14</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YHR023W
Gene name MYO1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:151666..157452
Primary SGDID S000001065


Description of YHR023W: Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively[1][2][3][4]




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Community Commentary

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Interactions

Genetic

Genetic interaction with hof1
Phenotype(s): Synthetic Lethal with hof1 Mutation type(s): deletion, deletion

[5] [6]




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References

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  1. Bi E, et al. (1998) Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. J Cell Biol 142(5):1301-12 SGD PMID 9732290
  2. Brown SS (1997) Myosins in yeast. Curr Opin Cell Biol 9(1):44-8 SGD PMID 9013666
  3. Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 SGD PMID 15210731
  4. Tolliday N, et al. (2003) Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Mol Biol Cell 14(2):798-809 SGD PMID 12589071
  5. Vallen EA, et al. (2000) Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae. Mol Biol Cell 11(2):593-611 SGD PMID 10679017
  6. submitted by Erfei Bi on 2003-08-14

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