YGR246C

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Systematic name YGR246C
Gene name BRF1
Aliases PCF4, TDS4
Feature type ORF, Verified
Coordinates Chr VII:984277..982487
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Description of YGR246C: TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB[1][2][3]



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References

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  1. Kassavetis GA, et al. (1998) Functional and structural organization of Brf, the TFIIB-related component of the RNA polymerase III transcription initiation complex. Mol Cell Biol 18(9):5587-99 SGD PMID 9710642
  2. Khoo B, et al. (1994) Conserved functional domains of the RNA polymerase III general transcription factor BRF. Genes Dev 8(23):2879-90 SGD PMID 7995525
  3. Kassavetis GA, et al. (1997) Domains of the Brf component of RNA polymerase III transcription factor IIIB (TFIIIB): functions in assembly of TFIIIB-DNA complexes and recruitment of RNA polymerase to the promoter. Mol Cell Biol 17(9):5299-306 SGD PMID 9271407

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