Difference between revisions of "YGR198W"
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| − | '''Description of YGR198W:''' Cargo-transport protein involved in endocytosis; | + | '''Description of YGR198W:''' Cargo-transport protein involved in endocytosis; interacts with phosphatidylinositol-4-kinase Stt4; GFP-fusion protein localizes to the cytoplasm; YGR198W is an essential gene<ref name='S000126928'>Zhai C, et al. (2008) Ypp1/YGR198w plays an essential role in phosphoinositide signalling at the plasma membrane. Biochem J 415(3):455-66 {{SGDpaper|S000126928}} PMID 18601652</ref><ref name='S000123065'>Flower TR, et al. (2007) YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation. J Cell Biol 177(6):1091-104 {{SGDpaper|S000123065}} PMID 17576801</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000047842'>Rodriguez-Pena JM, et al. (1998) The deletion of six ORFs of unknown function from Saccharomyces cerevisiae chromosome VII reveals two essential genes: YGR195w and YGR198w. Yeast 14(9):853-60 |
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Revision as of 07:21, 26 February 2009
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR198W |
| Gene name | YPP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:894698..897151 |
| Primary SGDID | S000003430 |
Description of YGR198W: Cargo-transport protein involved in endocytosis; interacts with phosphatidylinositol-4-kinase Stt4; GFP-fusion protein localizes to the cytoplasm; YGR198W is an essential gene[1][2][3][4]
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Community Commentary
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GFP-tag is more effective at the n-terminal end. Adding an epitope tag at the C-terminus makes the strain somewhat sick and lowers PI4P levels, however, it seems to localize correctly.
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References
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- ↑ Zhai C, et al. (2008) Ypp1/YGR198w plays an essential role in phosphoinositide signalling at the plasma membrane. Biochem J 415(3):455-66 SGD PMID 18601652
- ↑ Flower TR, et al. (2007) YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation. J Cell Biol 177(6):1091-104 SGD PMID 17576801
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Rodriguez-Pena JM, et al. (1998) The deletion of six ORFs of unknown function from Saccharomyces cerevisiae chromosome VII reveals two essential genes: YGR195w and YGR198w. Yeast 14(9):853-60 SGD PMID 9818723
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References
See Help:References on how to add references
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
