Difference between revisions of "YGR118W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003350 YGR118W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003350 YGR118W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPS23A ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPS23A ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:726978..727735
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|nowrap| Chr VII:726974..727730
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003350
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003350
 
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'''Description of YGR118W:''' Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal<ref name='S000074367'>Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 {{SGDpaper|S000074367}} PMID 12490706</ref><ref name='S000057772'>Alksne LE and Warner JR (1993) A novel cloning strategy reveals the gene for the yeast homologue to Escherichia coli ribosomal protein S12. J Biol Chem 268(15):10813-9 {{SGDpaper|S000057772}} PMID 8496146</ref><ref name='S000041585'>Synetos D, et al. (1996) Mutations in yeast ribosomal proteins S28 and S4 affect the accuracy of translation and alter the sensitivity of the ribosomes to paromomycin. Biochim Biophys Acta 1309(1-2):156-66
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'''Description of YGR118W:''' Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; homologous to mammalian ribosomal protein S23 and bacterial S12; RPS23A has a paralog, RPS23B, that arose from the whole genome duplication; deletion of both RPS23A and RPS23B is lethal<ref name='S000057772'>Alksne LE and Warner JR (1993) A novel cloning strategy reveals the gene for the yeast homologue to Escherichia coli ribosomal protein S12. J Biol Chem 268(15):10813-9 {{SGDpaper|S000057772}} PMID 8496146</ref><ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000150523'>Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () {{SGDpaper|S000150523}} PMID 22884264</ref><ref name='S000074367'>Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 {{SGDpaper|S000074367}} PMID 12490706</ref><ref name='S000041585'>Synetos D, et al. (1996) Mutations in yeast ribosomal proteins S28 and S4 affect the accuracy of translation and alter the sensitivity of the ribosomes to paromomycin. Biochim Biophys Acta 1309(1-2):156-66
 
  {{SGDpaper|S000041585}} PMID 8950190</ref>
 
  {{SGDpaper|S000041585}} PMID 8950190</ref>
 
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Latest revision as of 14:05, 17 September 2012

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Systematic name YGR118W
Gene name RPS23A
Aliases
Feature type ORF, Verified
Coordinates Chr VII:726974..727730
Primary SGDID S000003350


Description of YGR118W: Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; homologous to mammalian ribosomal protein S23 and bacterial S12; RPS23A has a paralog, RPS23B, that arose from the whole genome duplication; deletion of both RPS23A and RPS23B is lethal[1][2][3][4][5]




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References

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  1. Alksne LE and Warner JR (1993) A novel cloning strategy reveals the gene for the yeast homologue to Escherichia coli ribosomal protein S12. J Biol Chem 268(15):10813-9 SGD PMID 8496146
  2. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  3. Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () SGD PMID 22884264
  4. Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 SGD PMID 12490706
  5. Synetos D, et al. (1996) Mutations in yeast ribosomal proteins S28 and S4 affect the accuracy of translation and alter the sensitivity of the ribosomes to paromomycin. Biochim Biophys Acta 1309(1-2):156-66 SGD PMID 8950190

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