YGL175C
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| Systematic name | YGL175C |
| Gene name | SAE2 |
| Aliases | COM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:174328..173291 |
Description of YGL175C: Protein with a role in accurate meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents[1][2][3][4][5]
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Contents
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References
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- ↑ Baroni E, et al. (2004) The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol Cell Biol 24(10):4151-65 SGD PMID 15121837
- ↑ Rattray AJ, et al. (2001) Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1. Genetics 158(1):109-22 SGD PMID 11333222
- ↑ McKee AH and Kleckner N (1997) Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3. Genetics 146(3):817-34 SGD PMID 9215889
- ↑ McKee AH and Kleckner N (1997) A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2. Genetics 146(3):797-816 SGD PMID 9215888
- ↑ Prinz S, et al. (1997) Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. Genetics 146(3):781-95 SGD PMID 9215887
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