Difference between revisions of "YGL175C"
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| − | '''Description of YGL175C:''' | + | '''Description of YGL175C:''' Endonuclease that processes hairpin DNA structures with the MRX complex; involved in meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents<ref name='S000124863'>Lengsfeld BM, et al. (2007) Sae2 Is an Endonuclease that Processes Hairpin DNA Cooperatively with the Mre11/Rad50/Xrs2 Complex. Mol Cell 28(4):638-51 {{SGDpaper|S000124863}} PMID 18042458</ref><ref name='S000076515'>Baroni E, et al. (2004) The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol Cell Biol 24(10):4151-65 {{SGDpaper|S000076515}} PMID 15121837</ref><ref name='S000060386'>Rattray AJ, et al. (2001) Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1. Genetics 158(1):109-22 {{SGDpaper|S000060386}} PMID 11333222</ref><ref name='S000045008'>McKee AH and Kleckner N (1997) A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2. Genetics 146(3):797-816 {{SGDpaper|S000045008}} PMID 9215888</ref><ref name='S000045005'>Prinz S, et al. (1997) Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. Genetics 146(3):781-95 |
{{SGDpaper|S000045005}} PMID 9215887</ref> | {{SGDpaper|S000045005}} PMID 9215887</ref> | ||
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Revision as of 14:05, 1 May 2008
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| Systematic name | YGL175C |
| Gene name | SAE2 |
| Aliases | COM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:174328..173291 |
| Primary SGDID | S000003143 |
Description of YGL175C: Endonuclease that processes hairpin DNA structures with the MRX complex; involved in meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents[1][2][3][4][5]
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References
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- ↑ Lengsfeld BM, et al. (2007) Sae2 Is an Endonuclease that Processes Hairpin DNA Cooperatively with the Mre11/Rad50/Xrs2 Complex. Mol Cell 28(4):638-51 SGD PMID 18042458
- ↑ Baroni E, et al. (2004) The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol Cell Biol 24(10):4151-65 SGD PMID 15121837
- ↑ Rattray AJ, et al. (2001) Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1. Genetics 158(1):109-22 SGD PMID 11333222
- ↑ McKee AH and Kleckner N (1997) A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2. Genetics 146(3):797-816 SGD PMID 9215888
- ↑ Prinz S, et al. (1997) Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. Genetics 146(3):781-95 SGD PMID 9215887
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