YFL026W

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Systematic name YFL026W
Gene name STE2
Aliases
Feature type ORF, Verified
Coordinates Chr VI:82578..83873
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Description of YFL026W: Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells[1][2][3]



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References

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  1. Jenness DD, et al. (1986) Binding of alpha-factor pheromone to Saccharomyces cerevisiae a cells: dissociation constant and number of binding sites. Mol Cell Biol 6(1):318-20 SGD PMID 3023832
  2. Burkholder AC and Hartwell LH (1985) The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene. Nucleic Acids Res 13(23):8463-75 SGD PMID 3001640
  3. Blumer KJ and Thorner J (1990) Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proc Natl Acad Sci U S A 87(11):4363-7 SGD PMID 2161538

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