YER178W

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Systematic name YER178W
Gene name PDA1
Aliases
Feature type ORF, Verified
Coordinates Chr V:546812..548074
Primary SGDID S000000980


Description of YER178W: E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose[1][2][3][4]




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References

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  1. Steensma HY, et al. (1990) Molecular cloning of the gene for the E1 alpha subunit of the pyruvate dehydrogenase complex from Saccharomyces cerevisiae. Eur J Biochem 191(3):769-74 SGD PMID 2202601
  2. Sierkstra LN, et al. (1992) Analysis of transcription and translation of glycolytic enzymes in glucose-limited continuous cultures of Saccharomyces cerevisiae. J Gen Microbiol 138(12):2559-66 SGD PMID 1487726
  3. Pronk JT, et al. (1996) Pyruvate metabolism in Saccharomyces cerevisiae. Yeast 12(16):1607-33 SGD PMID 9123965
  4. Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666

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