Difference between revisions of "YER162C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YER162C YER162C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000964 YER162C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD4 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr V:502889..500625
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|nowrap| Chr V:502894..500630
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000964
 
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'''Description of {{PAGENAME}}:''' Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein<ref name='S000074162'>de Laat WL, et al. (1999) Molecular mechanism of nucleotide excision repair. Genes Dev 13(7):768-85 {{SGDpaper|S000074162}} PMID 10197977</ref><ref name='S000073199'>Lommel L, et al. (2002) Proteolysis of a nucleotide excision repair protein by the 26 S proteasome. Curr Genet 42(1):9-20 {{SGDpaper|S000073199}} PMID 12420141</ref><ref name='S000070118'>Prakash S and Prakash L (2000) Nucleotide excision repair in yeast. Mutat Res 451(1-2):13-24
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'''Description of YER162C:''' Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); also involved, with Rad23p, in turnover of ubiquitylated proteins<ref name='S000134867'>Li Y, et al. (2010) Rad4 regulates protein turnover at a postubiquitylation step. Mol Biol Cell 21(1):177-85 {{SGDpaper|S000134867}} PMID 19889839</ref><ref name='S000073199'>Lommel L, et al. (2002) Proteolysis of a nucleotide excision repair protein by the 26 S proteasome. Curr Genet 42(1):9-20 {{SGDpaper|S000073199}} PMID 12420141</ref><ref name='S000070118'>Prakash S and Prakash L (2000) Nucleotide excision repair in yeast. Mutat Res 451(1-2):13-24 {{SGDpaper|S000070118}} PMID 10915862</ref><ref name='S000074162'>de Laat WL, et al. (1999) Molecular mechanism of nucleotide excision repair. Genes Dev 13(7):768-85
  {{SGDpaper|S000070118}} PMID 10915862</ref>
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  {{SGDpaper|S000074162}} PMID 10197977</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YER162C
Gene name RAD4
Aliases
Feature type ORF, Verified
Coordinates Chr V:502894..500630
Primary SGDID S000000964


Description of YER162C: Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); also involved, with Rad23p, in turnover of ubiquitylated proteins[1][2][3][4]




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References

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  1. Li Y, et al. (2010) Rad4 regulates protein turnover at a postubiquitylation step. Mol Biol Cell 21(1):177-85 SGD PMID 19889839
  2. Lommel L, et al. (2002) Proteolysis of a nucleotide excision repair protein by the 26 S proteasome. Curr Genet 42(1):9-20 SGD PMID 12420141
  3. Prakash S and Prakash L (2000) Nucleotide excision repair in yeast. Mutat Res 451(1-2):13-24 SGD PMID 10915862
  4. de Laat WL, et al. (1999) Molecular mechanism of nucleotide excision repair. Genes Dev 13(7):768-85 SGD PMID 10197977

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