Difference between revisions of "YER147C"
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| − | '''Description of YER147C:''' Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX<ref name='S000060398'>Ciosk R, et al. (2000) Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol Cell 5(2):243-54 {{SGDpaper|S000060398}} PMID 10882066</ref><ref name=' | + | '''Description of YER147C:''' Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX<ref name='S000060398'>Ciosk R, et al. (2000) Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol Cell 5(2):243-54 {{SGDpaper|S000060398}} PMID 10882066</ref><ref name='S000080735'>Strom L, et al. (2004) Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair. Mol Cell 16(6):1003-15 {{SGDpaper|S000080735}} PMID 15610742</ref><ref name='S000080063'>Unal E, et al. (2004) DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol Cell 16(6):991-1002 |
| − | {{SGDpaper| | + | {{SGDpaper|S000080063}} PMID 15610741</ref> |
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Revision as of 14:05, 25 February 2010
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| Systematic name | YER147C |
| Gene name | SCC4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:464837..462963 |
| Primary SGDID | S000000949 |
Description of YER147C: Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX[1][2][3]
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References
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- ↑ Ciosk R, et al. (2000) Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol Cell 5(2):243-54 SGD PMID 10882066
- ↑ Strom L, et al. (2004) Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair. Mol Cell 16(6):1003-15 SGD PMID 15610742
- ↑ Unal E, et al. (2004) DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol Cell 16(6):991-1002 SGD PMID 15610741
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