Difference between revisions of "YER048W-A"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000007237 YER048W-A] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ISD11 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ISD11 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr V: | + | |nowrap| Chr V:250718..251002 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000007237 | ||
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| − | '''Description of | + | '''Description of YER048W-A:''' Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis<ref name='S000113860'>Adam AC, et al. (2006) The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J 25(1):174-83 {{SGDpaper|S000113860}} PMID 16341090</ref><ref name='S000146765'>Pandey A, et al. (2011) Isd11p activates the mitochondrial cysteine desulfurase, Nfs1p. J Biol Chem () {{SGDpaper|S000146765}} PMID 21908622</ref><ref name='S000120450'>Wiedemann N, et al. (2006) Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J 25(1):184-95 |
| − | {{SGDpaper| | + | {{SGDpaper|S000120450}} PMID 16341089</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YER048W-A |
| Gene name | ISD11 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:250718..251002 |
| Primary SGDID | S000007237 |
Description of YER048W-A: Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis[1][2][3]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Adam AC, et al. (2006) The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J 25(1):174-83 SGD PMID 16341090
- ↑ Pandey A, et al. (2011) Isd11p activates the mitochondrial cysteine desulfurase, Nfs1p. J Biol Chem () SGD PMID 21908622
- ↑ Wiedemann N, et al. (2006) Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J 25(1):184-95 SGD PMID 16341089
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