Difference between revisions of "YDR519W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YDR519W
Gene name FPR2
Aliases FKB2
Feature type ORF, Verified
Coordinates Chr IV:1480417..1480824


Description of YDR519W: Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking[1][2][3]




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References

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  1. Nielsen JB, et al. (1992) Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. Proc Natl Acad Sci U S A 89(16):7471-5 SGD PMID 1380159
  2. Partaledis JA, et al. (1992) Saccharomyces cerevisiae contains a homolog of human FKBP-13, a membrane-associated FK506/rapamycin binding protein. Yeast 8(8):673-80 SGD PMID 1279908
  3. Partaledis JA and Berlin V (1993) The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum. Proc Natl Acad Sci U S A 90(12):5450-4 SGD PMID 7685904

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