Difference between revisions of "YDR390C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YDR390C
Gene name UBA2
Aliases UAL1
Feature type ORF, Verified
Coordinates Chr IV:1256839..1254929


Description of YDR390C: Nuclear protein that acts as a heterodimer with Aos1p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability[1][2]




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References

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  1. Johnson ES, et al. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J 16(18):5509-19 SGD PMID 9312010
  2. Dohmen RJ, et al. (1995) An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. J Biol Chem 270(30):18099-109 SGD PMID 7629121

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