Difference between revisions of "YDR390C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002798 YDR390C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''UBA2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''UBA2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:1256847..1254937 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002798 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002798 | ||
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<br> | <br> | ||
| − | '''Description of YDR390C:''' | + | '''Description of YDR390C:''' Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability<ref name='S000039750'>Dohmen RJ, et al. (1995) An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. J Biol Chem 270(30):18099-109 {{SGDpaper|S000039750}} PMID 7629121</ref><ref name='S000040819'>Johnson ES, et al. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J 16(18):5509-19 |
{{SGDpaper|S000040819}} PMID 9312010</ref> | {{SGDpaper|S000040819}} PMID 9312010</ref> | ||
<br> | <br> | ||
Latest revision as of 07:45, 23 January 2012
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| Systematic name | YDR390C |
| Gene name | UBA2 |
| Aliases | UAL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1256847..1254937 |
| Primary SGDID | S000002798 |
Description of YDR390C: Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability[1][2]
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References
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- ↑ Dohmen RJ, et al. (1995) An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. J Biol Chem 270(30):18099-109 SGD PMID 7629121
- ↑ Johnson ES, et al. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J 16(18):5509-19 SGD PMID 9312010
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