Difference between revisions of "YDR353W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002761 YDR353W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002761 YDR353W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRR1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRR1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:1183293..1184252
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|nowrap| Chr IV:1183299..1184258
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002761
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002761
 
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'''Description of YDR353W:''' Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress<ref name='S000073788'>Trotter EW and Grant CM (2003) Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems. EMBO Rep 4(2):184-8 {{SGDpaper|S000073788}} PMID 12612609</ref><ref name='S000071764'>Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 {{SGDpaper|S000071764}} PMID 12410842</ref><ref name='S000059335'>Ross SJ, et al. (2000) Thioredoxin peroxidase is required for the transcriptional response to oxidative stress in budding yeast. Mol Biol Cell 11(8):2631-42 {{SGDpaper|S000059335}} PMID 10930459</ref><ref name='S000049388'>Machado AK, et al. (1997) Thioredoxin reductase-dependent inhibition of MCB cell cycle box activity in Saccharomyces cerevisiae. J Biol Chem 272(27):17045-54 {{SGDpaper|S000049388}} PMID 9202020</ref><ref name='S000047291'>Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73
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'''Description of YDR353W:''' Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress<ref name='S000049388'>Machado AK, et al. (1997) Thioredoxin reductase-dependent inhibition of MCB cell cycle box activity in Saccharomyces cerevisiae. J Biol Chem 272(27):17045-54 {{SGDpaper|S000049388}} PMID 9202020</ref><ref name='S000047291'>Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 {{SGDpaper|S000047291}} PMID 10037727</ref><ref name='S000059335'>Ross SJ, et al. (2000) Thioredoxin peroxidase is required for the transcriptional response to oxidative stress in budding yeast. Mol Biol Cell 11(8):2631-42 {{SGDpaper|S000059335}} PMID 10930459</ref><ref name='S000071764'>Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 {{SGDpaper|S000071764}} PMID 12410842</ref><ref name='S000073788'>Trotter EW and Grant CM (2003) Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems. EMBO Rep 4(2):184-8
  {{SGDpaper|S000047291}} PMID 10037727</ref>
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  {{SGDpaper|S000073788}} PMID 12612609</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YDR353W
Gene name TRR1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1183299..1184258
Primary SGDID S000002761


Description of YDR353W: Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress[1][2][3][4][5]




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References

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  1. Machado AK, et al. (1997) Thioredoxin reductase-dependent inhibition of MCB cell cycle box activity in Saccharomyces cerevisiae. J Biol Chem 272(27):17045-54 SGD PMID 9202020
  2. Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 SGD PMID 10037727
  3. Ross SJ, et al. (2000) Thioredoxin peroxidase is required for the transcriptional response to oxidative stress in budding yeast. Mol Biol Cell 11(8):2631-42 SGD PMID 10930459
  4. Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 SGD PMID 12410842
  5. Trotter EW and Grant CM (2003) Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems. EMBO Rep 4(2):184-8 SGD PMID 12612609

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