Difference between revisions of "YDR044W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002451 YDR044W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HEM13 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HEM13 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr IV:546640..547626 | |nowrap| Chr IV:546640..547626 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002451 | ||
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| − | '''Description of | + | '''Description of YDR044W:''' Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)<ref name='S000063438'>Grandchamp B, et al. (1978) The mitochondrial localization of coproporphyrinogen III oxidase. Biochem J 176(1):97-102 {{SGDpaper|S000063438}} PMID 31872</ref><ref name='S000057328'>Urban-Grimal D and Labbe-Bois R (1981) Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis. Mol Gen Genet 183(1):85-92 {{SGDpaper|S000057328}} PMID 7035824</ref><ref name='S000047239'>Zagorec M, et al. (1988) Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase. J Biol Chem 263(20):9718-24 {{SGDpaper|S000047239}} PMID 2838478</ref><ref name='S000041863'>Keng T (1992) HAP1 and ROX1 form a regulatory pathway in the repression of HEM13 transcription in Saccharomyces cerevisiae. Mol Cell Biol 12(6):2616-23 {{SGDpaper|S000041863}} PMID 1588959</ref><ref name='S000040696'>Amillet JM, et al. (1995) Positive and negative elements involved in the differential regulation by heme and oxygen of the HEM13 gene (coproporphyrinogen oxidase) in Saccharomyces cerevisiae. Curr Genet 28(6):503-11 |
{{SGDpaper|S000040696}} PMID 8593679</ref> | {{SGDpaper|S000040696}} PMID 8593679</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR044W |
| Gene name | HEM13 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:546640..547626 |
| Primary SGDID | S000002451 |
Description of YDR044W: Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)[1][2][3][4][5]
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References
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- ↑ Grandchamp B, et al. (1978) The mitochondrial localization of coproporphyrinogen III oxidase. Biochem J 176(1):97-102 SGD PMID 31872
- ↑ Urban-Grimal D and Labbe-Bois R (1981) Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis. Mol Gen Genet 183(1):85-92 SGD PMID 7035824
- ↑ Zagorec M, et al. (1988) Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase. J Biol Chem 263(20):9718-24 SGD PMID 2838478
- ↑ Keng T (1992) HAP1 and ROX1 form a regulatory pathway in the repression of HEM13 transcription in Saccharomyces cerevisiae. Mol Cell Biol 12(6):2616-23 SGD PMID 1588959
- ↑ Amillet JM, et al. (1995) Positive and negative elements involved in the differential regulation by heme and oxygen of the HEM13 gene (coproporphyrinogen oxidase) in Saccharomyces cerevisiae. Curr Genet 28(6):503-11 SGD PMID 8593679
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