YBR278W

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Systematic name YBR278W
Gene name DPB3
Aliases
Feature type ORF, Verified
Coordinates Chr II:760290..760895


Description of YBR278W: Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle[1][2][3]




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References

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  1. Iida T and Araki H (2004) Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 24(1):217-27 SGD PMID 14673157
  2. Li Y, et al. (2000) Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem 275(30):23247-52 SGD PMID 10801849
  3. Araki H, et al. (1991) Cloning DPB3, the gene encoding the third subunit of DNA polymerase II of Saccharomyces cerevisiae. Nucleic Acids Res 19(18):4867-72 SGD PMID 1923754

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