YOR209C
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Systematic name | YOR209C | |
Gene name | NPT1 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr XV:737727..736438 | |
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Description of YOR209C: Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus[1][2]
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References
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- ↑ Anderson RM, et al. (2002) Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels. J Biol Chem 277(21):18881-90 SGD PMID 11884393
- ↑ Smith JS, et al. (2000) A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A 97(12):6658-63 SGD PMID 10841563
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