YOR083W

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Systematic name YOR083W
Gene name WHI5
Aliases
Feature type ORF, Verified
Coordinates Chr XV:479535..480422
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Description of YOR083W: Repressor of G1 transcription that binds to SCB binding factor (SBF) at SCB target promoters in early G1; phosphorylation of Whi5p by the CDK, Cln3p/Cdc28p relieves repression and promoter binding by Whi5; periodically expressed in G1[1][2][3][4]



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References

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  1. Costanzo M, et al. (2004) CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast. Cell 117(7):899-913 SGD PMID 15210111
  2. de Bruin RA, et al. (2004) Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5. Cell 117(7):887-98 SGD PMID 15210110
  3. Jorgensen P, et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400 SGD PMID 12089449
  4. Spellman PT, et al. (1998) Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol Biol Cell 9(12):3273-97 SGD PMID 9843569

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