YMR139W
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| Systematic name | YMR139W | |
| Gene name | RIM11 | |
| Aliases | GSK3, MDS1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XIII:546124..547236 | |
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Description of YMR139W: Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta[1][2][3]
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References
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- ↑ Rubin-Bejerano I, et al. (2004) The in vivo activity of Ime1, the key transcriptional activator of meiosis-specific genes in Saccharomyces cerevisiae, is inhibited by the cyclic AMP/protein kinase A signal pathway through the glycogen synthase kinase 3-beta homolog Rim11. Mol Cell Biol 24(16):6967-79 SGD PMID 15282298
- ↑ Puziss JW, et al. (1994) MDS1, a dosage suppressor of an mck1 mutant, encodes a putative yeast homolog of glycogen synthase kinase 3. Mol Cell Biol 14(1):831-9 SGD PMID 8264650
- ↑ Malathi K, et al. (1997) Interaction of yeast repressor-activator protein Ume6p with glycogen synthase kinase 3 homolog Rim11p. Mol Cell Biol 17(12):7230-6 SGD PMID 9372955
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