YLR452C

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Systematic name YLR452C
Gene name SST2
Aliases
Feature type ORF, Verified
Coordinates Chr XII:1041364..1039268
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Description of YLR452C: GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family[1][2][3]



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References

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  1. Siderovski DP, et al. (1996) A new family of regulators of G-protein-coupled receptors? Curr Biol 6(2):211-2 SGD PMID 8673468
  2. Siekhaus DE and Drubin DG (2003) Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant. Nat Cell Biol 5(3):231-5 SGD PMID 12598904
  3. Apanovitch DM, et al. (1998) Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast. Biochemistry 37(14):4815-22 SGD PMID 9537998

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