YLR336C

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Systematic name YLR336C
Gene name SGD1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:802396..799697
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Description of YLR336C: Essential nuclear protein with a possible role in the osmoregulatory glycerol response; interacts with phospholipase C (Plc1p); putative homolog of human NOM1 which is implicated in acute myeloid leukemia[1][2][3]



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References

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  1. Simmons HM, et al. (2005) Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. Gene 347(1):137-45 SGD PMID 15715967
  2. Lin H, et al. (2002) Phospholipase C interacts with Sgd1p and is required for expression of GPD1 and osmoresistance in Saccharomyces cerevisiae. Mol Genet Genomics 267(3):313-20 SGD PMID 12073033
  3. Akhtar N, et al. (2000) SGD1 encodes an essential nuclear protein of Saccharomyces cerevisiae that affects expression of the GPD1 gene for glycerol 3-phosphate dehydrogenase. FEBS Lett 483(2-3):87-92 SGD PMID 11042259

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