YGR047C

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Systematic name YGR047C
Gene name TFC4
Aliases PCF1
Feature type ORF, Verified
Coordinates Chr VII:589473..586396
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Description of YGR047C: One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102[1][2][3]



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References

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  1. Geiduschek EP and Kassavetis GA (2001) The RNA polymerase III transcription apparatus. J Mol Biol 310(1):1-26 SGD PMID 11419933
  2. Marck C, et al. (1993) The TFIIIB-assembling subunit of yeast transcription factor TFIIIC has both tetratricopeptide repeats and basic helix-loop-helix motifs. Proc Natl Acad Sci U S A 90(9):4027-31 SGD PMID 8387209
  3. Bartholomew B, et al. (1991) Two components of Saccharomyces cerevisiae transcription factor IIIB (TFIIIB) are stereospecifically located upstream of a tRNA gene and interact with the second-largest subunit of TFIIIC. Mol Cell Biol 11(10):5181-9 SGD PMID 1922038

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