YPL262W

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Systematic name YPL262W
Gene name FUM1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:47336..48802
Primary SGDID S000006183


Description of YPL262W: Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation[1][2]




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References

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  1. Sass E, et al. (2003) Folding of fumarase during mitochondrial import determines its dual targeting in yeast. J Biol Chem 278(46):45109-16 SGD PMID 12960177
  2. Przybyla-Zawislak B, et al. (1999) Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics 152(1):153-66 SGD PMID 10224250

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