YER019W
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| Systematic name | YER019W | |
| Gene name | ISC1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr V:192796..194229 | |
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Description of YER019W: Inositol phosphosphingolipid phospholipase C, hydrolyzes inositolphosphosphingolipids, activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol, mediates Na+ and Li+ halotolerance, contains a P loop-like domain[1][2][3]
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References
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- ↑ Okamoto Y, et al. (2002) Structural requirements for selective binding of ISC1 to anionic phospholipids. J Biol Chem 277(48):46470-7 SGD PMID 12244059
- ↑ Betz C, et al. (2002) ISC1-encoded inositol phosphosphingolipid phospholipase C is involved in Na+/Li+ halotolerance of Saccharomyces cerevisiae. Eur J Biochem 269(16):4033-9 SGD PMID 12180980
- ↑ Sawai H, et al. (2000) Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae. J Biol Chem 275(50):39793-8 SGD PMID 11006294
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