YOR140W

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Systematic name YOR140W
Gene name SFL1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:586982..589282


Description of YOR140W: Transcription repressor involved in regulation of flocculation-related genes, inhibits transcription by recruiting general corepressor Cyc8p-Tup1p to different promoters; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p[1][2][3][4]




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References

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  1. Pan X and Heitman J (2002) Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. Mol Cell Biol 22(12):3981-93 SGD PMID 12024012
  2. Conlan RS and Tzamarias D (2001) Sfl1 functions via the co-repressor Ssn6-Tup1 and the cAMP-dependent protein kinase Tpk2. J Mol Biol 309(5):1007-15 SGD PMID 11399075
  3. Fujita A, et al. (1989) Domains of the SFL1 protein of yeasts are homologous to Myc oncoproteins or yeast heat-shock transcription factor. Gene 85(2):321-8 SGD PMID 2697640
  4. Robertson LS and Fink GR (1998) The three yeast A kinases have specific signaling functions in pseudohyphal growth. Proc Natl Acad Sci U S A 95(23):13783-7 SGD PMID 9811878

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