YMR039C

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Systematic name YMR039C
Gene name SUB1
Aliases TSP1
Feature type ORF, Verified
Coordinates Chr XIII:349521..348643


Description of YMR039C: Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations[1][2]




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References

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  1. Calvo O and Manley JL (2005) The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription. EMBO J 24(5):1009-20 SGD PMID 15692559
  2. Wang JY, et al. (2004) The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage. Mol Cell Biol 24(13):6084-93 SGD PMID 15199162

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