YER101C

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Systematic name YER101C
Gene name AST2
Aliases
Feature type ORF, Verified
Coordinates Chr V:361794..360502
Primary SGDID S000000903


Description of YER101C: Similar to lipid raft associated protein Ast1p; similarly to Ast1p, overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily[1][2][3]




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References

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  1. Chang A and Fink GR (1995) Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole. J Cell Biol 128(1-2):39-49 SGD PMID 7822420
  2. Riveros-Rosas H, et al. (2003) Diversity, taxonomy and evolution of medium-chain dehydrogenase/reductase superfamily. Eur J Biochem 270(16):3309-34 SGD PMID 12899689
  3. SGD (2007) Information without a citation in SGD SGD PMID

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