YMR026C

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Systematic name YMR026C
Gene name PEX12
Aliases PAS11
Feature type ORF, Verified
Coordinates Chr XIII:325434..324235


Description of YMR026C: RING-finger peroxisomal membrane peroxin that plays an essential role in peroxisome biogenesis and peroxisomal matrix protein import, forms translocation subcomplex with Pex2p and Pex10p[1][2][3]




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References

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  1. Hazra PP, et al. (2002) Peroxisome remnants in pex3delta cells and the requirement of Pex3p for interactions between the peroxisomal docking and translocation subcomplexes. Traffic 3(8):560-74 SGD PMID 12121419
  2. Albertini M, et al. (2001) Pex12p of Saccharomyces cerevisiae is a component of a multi-protein complex essential for peroxisomal matrix protein import. Eur J Cell Biol 80(4):257-70 SGD PMID 11370741
  3. Chang CC, et al. (1997) Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders. Nat Genet 15(4):385-8 SGD PMID 9090384

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