YLR368W

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Systematic name YLR368W
Gene name MDM30
Aliases DSG1
Feature type ORF, Verified
Coordinates Chr XII:857540..859336
Primary SGDID S000004360


Description of YLR368W: F-box protein; associates with mitochondria and has a role in mitochondrial fusion; stimulates nuclear export of specific mRNAs; promotes ubiquitin-mediated degradation of Gal4p in some strains[1][2][3][4][5]




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References

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  1. Durr M, et al. (2006) Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast. Mol Biol Cell 17(9):3745-55 SGD PMID 16790496
  2. Fritz S, et al. (2003) Mdm30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast. Mol Biol Cell 14(6):2303-13 SGD PMID 12808031
  3. Muratani M, et al. (2005) The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing. Cell 120(6):887-99 SGD PMID 15797387
  4. Seol JH, et al. (2001) Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol 3(4):384-91 SGD PMID 11283612
  5. Shukla A, et al. (2009) Stimulation of mRNA export by an F-box protein, Mdm30p, in vivo. J Mol Biol 389(2):238-47 SGD PMID 19376128

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