YNL001W

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Systematic name YNL001W
Gene name DOM34
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:627459..628619
Primary SGDID S000004946


Description of YNL001W: Endoribonuclease; functions in no-go mRNA decay, protein translation to promote G1 progression and differentiation, required for meiotic cell division; similar to the eukaryotic Pelota[1][2][3][4]




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References

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  1. Ragan MA, et al. (1996) An archaebacterial homolog of pelota, a meiotic cell division protein in eukaryotes. FEMS Microbiol Lett 144(2-3):151-5 SGD PMID 8900058
  2. Davis L and Engebrecht J (1998) Yeast dom34 mutants are defective in multiple developmental pathways and exhibit decreased levels of polyribosomes. Genetics 149(1):45-56 SGD PMID 9584085
  3. Carr-Schmid A, et al. (2002) Novel G-protein complex whose requirement is linked to the translational status of the cell. Mol Cell Biol 22(8):2564-74 SGD PMID 11909951
  4. Lee HH, et al. (2007) Structural and functional insights into Dom34, a key component of no-go mRNA decay. Mol Cell 27(6):938-50 SGD PMID 17889667

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