YNL123W

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Systematic name YNL123W
Gene name NMA111
Aliases YNM3
Feature type ORF, Verified
Coordinates Chr XIV:394687..397680
Primary SGDID S000005067


Description of YNL123W: Serine protease and general molecular chaperone; involved in response to heat stress; may contribute to lipid homeostasis and/or apoptosis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases[1][2][3]




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References

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  1. Padmanabhan N, et al. (2009) The Yeast HtrA Orthologue Ynm3 Is a Protease with Chaperone Activity that Aids Survival Under Heat Stress. Mol Biol Cell 20(1):68-77 SGD PMID 18946088
  2. Fahrenkrog B, et al. (2004) The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J Cell Sci 117(Pt 1):115-26 SGD PMID 14657274
  3. Tong F, et al. (2006) Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis. Mol Genet Genomics 275(4):330-43 SGD PMID 16470384

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