YIL105C

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Systematic name YIL105C
Gene name SLM1
Aliases LIT2
Feature type ORF, Verified
Coordinates Chr IX:169638..167578
Primary SGDID S000001367


Description of YIL105C: Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; subunit of and phosphorylated by the TORC2 complex[1][2]




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References

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  1. Fadri M, et al. (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2. Mol Biol Cell 16(4):1883-900 SGD PMID 15689497
  2. Audhya A, et al. (2004) Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. EMBO J 23(19):3747-57 SGD PMID 15372071

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