Difference between revisions of "YNL163C"
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| − | '''Description of YNL163C:''' Cytoplasmic GTPase involved in biogenesis of the | + | '''Description of YNL163C:''' Cytoplasmic GTPase involved in ribosomal biogenesis; with Sdo1p, promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes<ref name='S000066242'>Becam AM, et al. (2001) Ria1p (Ynl163c), a protein similar to elongation factors 2, is involved in the biogenesis of the 60S subunit of the ribosome in Saccharomyces cerevisiae. Mol Genet Genomics 266(3):454-62 {{SGDpaper|S000066242}} PMID 11713675</ref><ref name='S000145759'>Finch AJ, et al. (2011) Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev 25(9):917-29 {{SGDpaper|S000145759}} PMID 21536732</ref><ref name='S000133608'>Gartmann M, et al. (2010) Mechanism of eIF6-mediated inhibition of ribosomal subunit joining. J Biol Chem 285(20):14848-51 {{SGDpaper|S000133608}} PMID 20356839</ref><ref name='S000121870'>Menne TF, et al. (2007) The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast. Nat Genet 39(4):486-95 {{SGDpaper|S000121870}} PMID 17353896</ref><ref name='S000068872'>Senger B, et al. (2001) The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis. Mol Cell 8(6):1363-73 |
{{SGDpaper|S000068872}} PMID 11779510</ref> | {{SGDpaper|S000068872}} PMID 11779510</ref> | ||
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Latest revision as of 14:05, 29 February 2012
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| Systematic name | YNL163C |
| Gene name | RIA1 |
| Aliases | EFL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:330073..326741 |
| Primary SGDID | S000005107 |
Description of YNL163C: Cytoplasmic GTPase involved in ribosomal biogenesis; with Sdo1p, promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes[1][2][3][4][5]
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References
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- ↑ Becam AM, et al. (2001) Ria1p (Ynl163c), a protein similar to elongation factors 2, is involved in the biogenesis of the 60S subunit of the ribosome in Saccharomyces cerevisiae. Mol Genet Genomics 266(3):454-62 SGD PMID 11713675
- ↑ Finch AJ, et al. (2011) Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev 25(9):917-29 SGD PMID 21536732
- ↑ Gartmann M, et al. (2010) Mechanism of eIF6-mediated inhibition of ribosomal subunit joining. J Biol Chem 285(20):14848-51 SGD PMID 20356839
- ↑ Menne TF, et al. (2007) The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast. Nat Genet 39(4):486-95 SGD PMID 17353896
- ↑ Senger B, et al. (2001) The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis. Mol Cell 8(6):1363-73 SGD PMID 11779510
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