Difference between revisions of "YJL138C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJL138C YJL138C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003674 YJL138C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TIF2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TIF2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr X:154688..153501
 
|nowrap| Chr X:154688..153501
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003674
 
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'''Description of {{PAGENAME}}:''' Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G<ref name='S000065400'>Caruthers JM, et al. (2000) Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase. Proc Natl Acad Sci U S A 97(24):13080-5 {{SGDpaper|S000065400}} PMID 11087862</ref><ref name='S000056850'>Chang TH, et al. (1990) Identification of five putative yeast RNA helicase genes. Proc Natl Acad Sci U S A 87(4):1571-5 {{SGDpaper|S000056850}} PMID 2406722</ref><ref name='S000056385'>Neff CL and Sachs AB (1999) Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionally. Mol Cell Biol 19(8):5557-64 {{SGDpaper|S000056385}} PMID 10409745</ref><ref name='S000048984'>Blum S, et al. (1989) Translation in Saccharomyces cerevisiae: initiation factor 4A-dependent cell-free system. Proc Natl Acad Sci U S A 86(16):6043-6
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'''Description of YJL138C:''' Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G<ref name='S000065400'>Caruthers JM, et al. (2000) Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase. Proc Natl Acad Sci U S A 97(24):13080-5 {{SGDpaper|S000065400}} PMID 11087862</ref><ref name='S000056850'>Chang TH, et al. (1990) Identification of five putative yeast RNA helicase genes. Proc Natl Acad Sci U S A 87(4):1571-5 {{SGDpaper|S000056850}} PMID 2406722</ref><ref name='S000056385'>Neff CL and Sachs AB (1999) Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionally. Mol Cell Biol 19(8):5557-64 {{SGDpaper|S000056385}} PMID 10409745</ref><ref name='S000048984'>Blum S, et al. (1989) Translation in Saccharomyces cerevisiae: initiation factor 4A-dependent cell-free system. Proc Natl Acad Sci U S A 86(16):6043-6
 
  {{SGDpaper|S000048984}} PMID 2668952</ref>
 
  {{SGDpaper|S000048984}} PMID 2668952</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:46, 27 February 2007

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Systematic name YJL138C
Gene name TIF2
Aliases
Feature type ORF, Verified
Coordinates Chr X:154688..153501
Primary SGDID S000003674


Description of YJL138C: Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G[1][2][3][4]




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References

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  1. Caruthers JM, et al. (2000) Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase. Proc Natl Acad Sci U S A 97(24):13080-5 SGD PMID 11087862
  2. Chang TH, et al. (1990) Identification of five putative yeast RNA helicase genes. Proc Natl Acad Sci U S A 87(4):1571-5 SGD PMID 2406722
  3. Neff CL and Sachs AB (1999) Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionally. Mol Cell Biol 19(8):5557-64 SGD PMID 10409745
  4. Blum S, et al. (1989) Translation in Saccharomyces cerevisiae: initiation factor 4A-dependent cell-free system. Proc Natl Acad Sci U S A 86(16):6043-6 SGD PMID 2668952

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