Difference between revisions of "YIL043C"
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| − | '''Description of YIL043C:''' Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia<ref name='S000119499'>Nussenzveig RH, et al. (2006) A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica 91(11):1542-5 {{SGDpaper|S000119499}} PMID 17082011</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000062023'>Csukai M, et al. (1994) Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae. Eur J Biochem 219(1-2):441-8 {{SGDpaper|S000062023}} PMID 8307010</ref><ref name='S000062022'>Kubota S, et al. (1977) Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase. J Biochem | + | '''Description of YIL043C:''' Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia<ref name='S000119499'>Nussenzveig RH, et al. (2006) A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica 91(11):1542-5 {{SGDpaper|S000119499}} PMID 17082011</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000062023'>Csukai M, et al. (1994) Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae. Eur J Biochem 219(1-2):441-8 {{SGDpaper|S000062023}} PMID 8307010</ref><ref name='S000062022'>Kubota S, et al. (1977) Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase. J Biochem 81(1):187-95 |
{{SGDpaper|S000062022}} PMID 14930</ref> | {{SGDpaper|S000062022}} PMID 14930</ref> | ||
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Revision as of 14:05, 22 December 2007
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| Systematic name | YIL043C |
| Gene name | CBR1 |
| Aliases | CBR5 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:274925..274071 |
| Primary SGDID | S000001305 |
Description of YIL043C: Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia[1][2][3][4]
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References
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- ↑ Nussenzveig RH, et al. (2006) A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica 91(11):1542-5 SGD PMID 17082011
- ↑ Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
- ↑ Csukai M, et al. (1994) Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae. Eur J Biochem 219(1-2):441-8 SGD PMID 8307010
- ↑ Kubota S, et al. (1977) Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase. J Biochem 81(1):187-95 SGD PMID 14930
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